CASP8 antibody - 100 µg

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Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: caspase 8, apoptosis-related cysteine peptidase
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 53-57 kDa, 32-45 kDa
Uniprot: Q14790
Gene id: 841
Background: Caspase 8, also named as MCH5, MACH, FLICE, and CAP4, belongs to the peptidase C14A family. It may participate in the GZMB apoptotic pathways and functions as an upstream regulator in a-bisabolol-induced apoptosis. Caspase 8 catalyzes an essential intermediate step in the ubiquitination and proteasome-mediated degradation of IRF3(PMID:21816816). It may control diabetic embryopathy-associated apoptosis via Caspase 8 is expressed as nine isoforms by alternative splicing with the molecular mass from 26 kDa to 62 kDa. This antibodycan recognize pro-and cleaved-caspase 8.
Field of research: Signal Transduction, Metabolism, cancer
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:2000; IHC: 1:50-1:500
Target: CASP8
Purification: Immunogen affinity purified
Reactivity: Human, Mouse

235.85 € 235.85 EUR 235.85 € VAT Excluded

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    Internal Reference: LM-19834
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