YTHDF1 antibody - 100 µg

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Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: YTH domain family, member 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 62 kDa
Uniprot: Q9BYJ9
Gene id: 54915
Background: Specifically recognizes and binds N6-methyladenosine(m6A)-containing mRNAs, and promotes mRNA translation efficiency(PubMed:24284625, PubMed:26046440, PubMed:26318451). M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability(PubMed:24284625). Acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3(EIF3A or EIF3B) to facilitate translation initiation(PubMed:26046440).
Field of research: Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IP
Dilution: WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:20-1:200
Target: YTHDF1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat

235.85 € 235.85 EUR 235.85 € VAT Excluded

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    Internal Reference: LM-19386
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