WEE2 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: WEE1 homolog 2(S. pombe)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 63 kDa
Uniprot: P0C1S8
Gene id: 494551
Background: Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle(GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation(By similarity).
Field of research: Developmental biology, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:200-1:2000
Target: WEE2
Purification: Immunogen affinity purified
Reactivity: Human
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: WEE1 homolog 2(S. pombe)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 63 kDa
Uniprot: P0C1S8
Gene id: 494551
Background: Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle(GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation(By similarity).
Field of research: Developmental biology, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:200-1:2000
Target: WEE2
Purification: Immunogen affinity purified
Reactivity: Human
Internal Reference:
LM-19321
Website URL:
/shop/lm-19321-wee2-antibody-100-ug-105242
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[LM-19321] WEE2 antibody - 100 µg
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