ULBP1 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: UL16 binding protein 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 30 kDa, 37 kDa
Uniprot: Q9BZM6
Gene id: 80329
Background: Ligand for the KLRK1
NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to KLRK1
NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase
Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the KLRK1
NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface.
Field of research: Cancer
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:200-1:2000; IHC: 1:20-1:200
Target: ULBP1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: UL16 binding protein 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 30 kDa, 37 kDa
Uniprot: Q9BZM6
Gene id: 80329
Background: Ligand for the KLRK1
NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to KLRK1
NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase
Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the KLRK1
NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface.
Field of research: Cancer
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:200-1:2000; IHC: 1:20-1:200
Target: ULBP1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse
Internal Reference:
LM-19067
Website URL:
/shop/lm-19067-ulbp1-antibody-100-ug-104988
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[LM-19067] ULBP1 antibody - 100 µg
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