TRIP4 antibody - 100 µg

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Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: thyroid hormone receptor interactor 4
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 66 kDa
Uniprot: Q15650
Gene id: 9325
Background: Transcription coactivator which associates with nuclear receptors, transcriptional coactivators including EP300, CREBBP and NCOA1, and basal transcription factors like TBP and TFIIA to facilitate nuclear receptors-mediated transcription. May thereby play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a role in thyroid hormone receptor and estrogen receptor transactivation(PubMed:10454579, PubMed:25219498). Also involved in androgen receptor transactivation(By similarity). Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B(PubMed:12077347). May play a role in the development of neuromuscular junction(PubMed:26924529).
Field of research: Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:5000
Target: TRIP4
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat

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