SMG5 antibody - 100 µg

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Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: Smg-5 homolog, nonsense mediated mRNA decay factor
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 114 kDa
Uniprot: Q9UPR3
Gene id: 23381
Background: Plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotes dephosphorylation of UPF1. Together with SMG7 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A(PP2A), thereby triggering UPF1 dephosphorylation. Necessary for TERT activity.
Field of research: Epigenetics
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: SMG5
Purification: Immunogen affinity purified
Reactivity: Human

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