PPARA antibody - 100 µg

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Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: peroxisome proliferator-activated receptor alpha
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 52-55 kDa
Uniprot: Q07869
Gene id: 5465
Background: Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine(16:0
18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
Field of research: Signal Transduction, Metabolism, Cardiovascular, Developmental biology, Neuroscience
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:200-1:1000; IHC: 1:50-1:200
Target: PPARA
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat

222.50 € 222.5 EUR 222.50 € VAT Excluded

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