IFT57 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: intraflagellar transport 57 homolog(Chlamydomonas)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 49 kDa
Uniprot: Q9NWB7
Gene id: 55081
Background: Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway(By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8(CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
Field of research: Neuroscience, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IP
Dilution: WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Target: IFT57
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: intraflagellar transport 57 homolog(Chlamydomonas)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 49 kDa
Uniprot: Q9NWB7
Gene id: 55081
Background: Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway(By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8(CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
Field of research: Neuroscience, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IP
Dilution: WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Target: IFT57
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
Internal Reference:
LM-14071
Website URL:
/shop/lm-14071-ift57-antibody-100-ug-99992
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[LM-14071] IFT57 antibody - 100 µg
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