CENPN antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: centromere protein N
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 40 kDa, 25-30 kDa
Uniprot: Q96H22
Gene id: 55839
Background: Component of the CENPA-NAC(nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD(nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPN is the first protein to bind specifically to CENPA nucleosomes and the direct binding of CENPA nucleosomes by CENPN is required for centromere assembly. Required for chromosome congression and efficiently align the chromosomes on a metaphase plate.
Field of research: Epigenetics
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: CENPN
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: centromere protein N
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 40 kDa, 25-30 kDa
Uniprot: Q96H22
Gene id: 55839
Background: Component of the CENPA-NAC(nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD(nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPN is the first protein to bind specifically to CENPA nucleosomes and the direct binding of CENPA nucleosomes by CENPN is required for centromere assembly. Required for chromosome congression and efficiently align the chromosomes on a metaphase plate.
Field of research: Epigenetics
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: CENPN
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
Internal Reference:
LM-11540
Website URL:
/shop/lm-11540-cenpn-antibody-100-ug-97461
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[LM-11540] CENPN antibody - 100 µg
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