BMI1 antibody - 100 µg

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Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: BMI1 polycomb ring finger oncogene
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 43-45 kDa
Uniprot: P35226
Gene id: 648
Background: Component of a Polycomb group(PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2
RING2.
Field of research: Epigenetics, Metabolism, Cancer, Developmental biology, Stem Cells, Cell Division and Proliferation
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IF, IP
Dilution: WB: 1:500-1:2000; IP: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100
Target: BMI1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse

235.85 € 235.85 EUR 235.85 € VAT Excluded

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    Internal Reference: LM-10878
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