BEX2 antibody - 100 µg

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Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: brain expressed X-linked 2
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 10-15 kDa
Uniprot: Q9BXY8
Gene id: 84707
Background: Regulator of mitochondrial apoptosis and G1 cell cycle in breast cancer. Protects the breast cancer cells against mitochondrial apoptosis and this effect is mediated through the modulation of BCL2 protein family, which involves the positive regulation of anti-apoptotic member BCL2 and the negative regulation of pro-apoptotic members BAD, BAK1 and PUMA. Required for the normal cell cycle progression during G1 in breast cancer cells through the regulation of CCND1 and CDKN1A. Regulates the level of PP2A regulatory subunit B and PP2A phosphatase activity. The homology between human BEX1 and BEX2 is 94%. This antibody detects both BEX1 and BEX2.
Field of research: Neuroscience, Signal Transduction, Cancer
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:1000; IHC: 1:20-1:200
Target: BEX2
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat

222.50 € 222.5 EUR 222.50 € VAT Excluded

222.50 € VAT Excluded

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