pHTS-Neo-GAS is a high-performance reporter plasmid designed for the study of gene activation and transcriptional regulation. This versatile system utilizes a Glucocorticoid Response Element (GRE)-based promoter linked to a luciferase reporter, providing a sensitive and quantitative readout of transcription factor activity. Ideal for screening gene activators and inhibitors, pHTS-Neo-GAS is optimized for high-throughput screening (HTS) applications, making it perfect for drug discovery, mechanistic studies, and the identification of potential therapeutic compounds. The system allows for precise monitoring of glucocorticoid receptor (GR)-mediated gene expression, offering a robust platform for research in hormone signaling, stress response, and cell signaling pathways. Available for use in various mammalian cell types, pHTS-Neo-GAS ensures reproducible and accurate results, enabling advanced research in molecular biology and drug development. - kit