pHTS-hygro-CRE is a high-performance cis element reporter plasmid specifically engineered with cAMP Response Element (CRE) sequences upstream of a luciferase reporter gene, enabling precise detection of CREB-mediated transcriptional activity. Designed for use in high-throughput screening (HTS) and signal transduction research, this vector is equipped with a hygromycin resistance marker for stable cell line selection. pHTS-hygro-CRE is ideal for studying cAMP/PKA signaling pathways, validating transcription factor activation, and analyzing promoter regulation in live cell assays. With its robust sensitivity, reproducible performance, and compatibility with various cell types, pHTS-hygro-CRE is the perfect choice for researchers investigating gene regulation, drug discovery, and pathway analysis. - kit