HSD17B10 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: hydroxysteroid(17-beta) dehydrogenase 10
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight:
Uniprot:
Gene id:
Background: Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1
TRMT10C, MRPP2
HSD17B10 and MRPP3
KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease(AD).
Field of research:
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Target: HSD17B10
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: hydroxysteroid(17-beta) dehydrogenase 10
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight:
Uniprot:
Gene id:
Background: Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1
TRMT10C, MRPP2
HSD17B10 and MRPP3
KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease(AD).
Field of research:
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Target: HSD17B10
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
Internal Reference:
LM-20489
Website URL:
/shop/lm-20489-hsd17b10-antibody-100-ug-106410
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[LM-20489] HSD17B10 antibody - 100 µg
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