WTAP antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 9D4
Isotype: IgG1
Immunogen: Wilms tumor 1 associated protein
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 49 kDa
Uniprot: Q15007
Gene id: 9589
Background: Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine(m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing, processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle(PubMed:24316715, PubMed:24407421, PubMed:24981863). Acts as a mRNA splicing regulator(PubMed:12444081). Regulates G2
M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability(PubMed:17088532). Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes(PubMed:17095724).
Field of research: Epigenetics
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:1000-1:10000; IHC: 1:50-1:500
Target: WTAP
Purification: Protein A+G purification
Reactivity: Human, Mouse, Rat
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Clonality: Monoclonal
Clone: 9D4
Isotype: IgG1
Immunogen: Wilms tumor 1 associated protein
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 49 kDa
Uniprot: Q15007
Gene id: 9589
Background: Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine(m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing, processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle(PubMed:24316715, PubMed:24407421, PubMed:24981863). Acts as a mRNA splicing regulator(PubMed:12444081). Regulates G2
M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability(PubMed:17088532). Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes(PubMed:17095724).
Field of research: Epigenetics
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:1000-1:10000; IHC: 1:50-1:500
Target: WTAP
Purification: Protein A+G purification
Reactivity: Human, Mouse, Rat
Internal Reference:
LM-19345
Website URL:
/shop/lm-19345-wtap-antibody-100-ug-105266
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[LM-19345] WTAP antibody - 100 µg
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