UNC13A antibody - 100 µg

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Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: unc-13 homolog A(C. elegans)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 193 kDa
Uniprot: Q9UPW8
Gene id: 23025
Background: UNC13A, also named as KIAA1032, belongs to the unc-13 family. It plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. UNC13A is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool(RRP). It is essential for synaptic vesicle maturation in most excitatory
glutamatergic but not inhibitory
GABA-mediated synapses. UNC13A is also involved in secretory granule priming in insulin secretion. The antibody is specific to UNC13A.
Field of research: Neuroscience, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:5000
Target: UNC13A
Purification: Immunogen affinity purified
Reactivity: Human, Mouse

249.20 € 249.20000000000002 EUR 249.20 € VAT Excluded

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    Internal Reference: LM-19073
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