TP63 antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 2A3
Isotype: IgG1
Immunogen: tumor protein p63
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 68 kDa
Uniprot: Q9H3D4
Gene id: 8626
Background: Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73
p73 for initiation of p53
TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter.
Field of research: Cancer
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: TP63
Purification: Protein A+G purification
Reactivity: Human
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Clonality: Monoclonal
Clone: 2A3
Isotype: IgG1
Immunogen: tumor protein p63
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 68 kDa
Uniprot: Q9H3D4
Gene id: 8626
Background: Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73
p73 for initiation of p53
TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter.
Field of research: Cancer
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: TP63
Purification: Protein A+G purification
Reactivity: Human
Internal Reference:
LM-18708
Website URL:
/shop/lm-18708-tp63-antibody-100-ug-104629
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[LM-18708] TP63 antibody - 100 µg
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