TLR3 antibody - 100 µg

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Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: toll-like receptor 3
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight:
Uniprot: O15455
Gene id: 7098
Background: Key component of innate and adaptive immunity. TLRs(Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF
TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response.
Field of research: Immunology, Signal Transduction, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC
Dilution: IHC: 1:20-1:200
Target: TLR3
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat

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