Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: TATA box binding protein
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 37-43 kDa
Uniprot: P20226
Gene id: 6908
Background: General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex(PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1
TIF-IB complex, which is involved in the assembly of the PIC(preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1
UBTF on rDNA.
Field of research: Neuroscience, Metabolism, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IP
Dilution: WB: 1:500-1:2000; IP: 1:200-1:2000
Target: TBP
Purification: Immunogen affinity purified
Reactivity: Human, Mouse