SYNGAP1 antibody - 100 µg

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Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: synaptic Ras GTPase activating protein 1 homolog(rat)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 148 kDa
Uniprot: Q96PV0
Gene id: 8831
Background: Major constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. Regulates AMPAR-mediated miniature excitatory postsynaptic currents. Exhibits dual GTPase-activating specificity for Ras and Rap. May be involved in certain forms of brain injury, leading to long-term learning and memory deficits(By similarity).
Field of research: Neuroscience, Cardiovascular, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IF
Dilution: WB: 1:500-1:2000; IF: 1:20-1:200
Target: SYNGAP1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat

235.85 € 235.85 EUR 235.85 € VAT Excluded

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