SOS1 antibody - 100 µg

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Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: son of sevenless homolog 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 180 kDa
Uniprot: Q07889
Gene id: 6654
Background: Promotes the exchange of Ras-bound GDP by GTP(PubMed:8493579). Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF(PubMed:17339331). Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor(GEF) activity(By similarity).
Field of research: cancer, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IF
Dilution: WB: 1:500 - 1:2000; IF: 1:50 - 1:100
Target: SOS1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat

235.85 € 235.85 EUR 235.85 € VAT Excluded

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