Slco4c1 antibody - 100 µg

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Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: solute carrier organic anion transporter family, member 4C1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 80 kDa
Uniprot: Q8BGD4
Gene id: 227394
Background: Organic anion transporter, capable of transporting pharmacological substances such as digoxin, ouabain, thyroxine, methotrexate and cAMP. May participate in the regulation of membrane transport of ouabain. Involved in the uptake of the dipeptidyl peptidase-4 inhibitor sitagliptin and hence may play a role in its transport into and out of renal proximal tubule cells. May be involved in the first step of the transport pathway of digoxin and various compounds into the urine in the kidney. May be involved in sperm maturation by enabling directed movement of organic anions and compounds within or between cells. This ion-transporting process is important to maintain the strict epididymal homeostasis necessary for sperm maturation. May have a role in secretory functions since seminal vesicle epithelial cells are assumed to secrete proteins involved in decapacitation by modifying surface proteins to facilitate the acquisition of the ability to fertilize the egg.
Field of research: Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:1000; IHC: 1:20-1:200
Target: Slco4c1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse

249.20 € 249.20000000000002 EUR 249.20 € VAT Excluded

249.20 € VAT Excluded

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