RASIP1 antibody - 100 µg

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Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: Ras interacting protein 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 115 kDa
Uniprot: Q5U651
Gene id: 54922
Background: Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells(By similarity). May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation. Negative regulator of amino acid starvation-induced autophagy.
Field of research: Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IF
Dilution: WB: 1:500-1:2000; IF: 1:20-1:200
Target: RASIP1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat

235.85 € 235.85 EUR 235.85 € VAT Excluded

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    Internal Reference: LM-16994
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