PDCD4 antibody - 100 µg

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Host : Mouse
Clonality: Monoclonal
Clone: 3B7
Isotype: IgG1
Immunogen: programmed cell death 4(neoplastic transformation inhibitor)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 56 kDa
Uniprot: Q53EL6
Gene id: 27250
Background: Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA(By similarity).
Field of research: Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:1000-1:4000; IHC: 1:20-1:200
Target: PDCD4
Purification: Protein A+G purification
Reactivity: Human

262.55 € 262.55 EUR 262.55 € VAT Excluded

262.55 € VAT Excluded

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