KPNA6 antibody - 100 µg

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Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: karyopherin alpha 6 (importin alpha 7)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 60 kDa
Uniprot: O60684
Gene id: 23633
Background: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family.
Field of research: Cancer, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC, WB
Dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Target: KPNA6
Purification: Immunogen affinity purified
Reactivity: Human, Mouse

249.20 € 249.20000000000002 EUR 249.20 € VAT Excluded

249.20 € VAT Excluded

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